Clinical Translation of Stem Cells in Neurodegenerative Disorders
نویسندگان
چکیده
منابع مشابه
Microglial cells in neurodegenerative disorders.
Microglia are resident immune cells of the CNS. They are involved in the pathogenesis of diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, prion diseases as well as multiple sclerosis, amyotrophic lateral sclerosis and AIDS dementia complex. It is widely accepted that microglia contribute to the neurodegeneration through a release of a variety of proinflammato...
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Stem cells are cells that have not yet differentiated to perform a certain task. Scientists and engineers can manipulate them to differentiate into a certain cell. This is advantageous for the scientific community because scientists, engineers, and doctors can use stem cells for their own reasons. They can be used to cure diseases or for research. Stem cells are a great way to cure certain dise...
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Bronwen Connor, Lecturer, Division of Pharmacology; Willeke MC van Roon-Mom, Assistant Research Fellow, Division of Anatomy with Radiology; Maurice A Curtis, PhD student, Division of Anatomy with Radiology; Michael Dragunow, Professor of Pharmacology, Division of Pharmacology; Richard LM Faull, Professor of Anatomy, Division of Anatomy with Radiology, Faculty of Medical and Health Sciences, Auc...
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Induced pluripotent stem cell (iPSC) technology has three major clinical applications in clinics: toxicology, drug screening, and regenerative medicine. Cardiac myocytes derived fromSCs have already been used in pharmaceutical companies to predict cardiac toxicity of drug candidates. Similar approach can be applied to other types of cells derived from iPSCs. Inmyopinion, themost promising appli...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2012
ISSN: 1934-5909
DOI: 10.1016/j.stem.2012.01.009